Hi Steve,
I go there every year, at least once - last year twice. I would suggest Gunnison. It's a town on HWY 50 - just west of Colorado Springs and Pueblo, with a population of about 6000.
I searched hotel / motel on google - there are 20 or so. Elevation arount 7,000 ft. Easy to get there - I-70 then thru the Springs. Only one high pass (Monarch) to go over using this route. Awesome rides - Pikes Peak, Million $ highway, Royal Gorge, etc., are all close.
The only challenge would be the timing. Too early - passes not open yet - too late...same thing. I would suggest late August to early September - not as many tourists, and a nice break from the heat when in the mountains. If you all decide to go, I would be glad to help.