Pains in the wrist? I have training in Ergonomics (big deal). This is occurring from wrist not being at zero degrees with stress for extended periods. So I am assuming your wrist was in the downward position while you were cranking the beast to 125 mph. Wrist position on our bikes is the same as in the office in the neutral position, which is flat where there is less strain. After adjusting the throttle to the desired position the wrist and palm should be adjusted to this neutral position. A Cramp Buster will allow you to rest your fingers from the death grip on the throttle and relax the hand.

Just food for thought. Ok, that's my two cents! Flame away.