All day comfort, is about taking the pressure off of certain points of your posterior, at different intervals. That's why I have 3 options. I usually change up at gas stops. My key to long distance riding, is consistency. I seldom go longer than 120 miles between gas/bathroom stops, and I don't spend longer than 10 minutes at each stop. I also spend that time hydrating and stretching, then it's back on the bike. YMMV, this is only my routine, and the reason I usually ride by myself.
I too, like the stock seat. however, I also change up with a mesh. It only raises the rider up less than 1/2 inch. I have a gel pad, but that raises me a good inch, comfy, but I have a 12" windshield, so that puts me up a bit too high. Consider your windshield height, before spending your $$. Also, your weight will vary the comfort level of the different types of seat pads.