I guess you can do about anything with enough money if you want. The question is why would yo want to? First the opening on the F6B is much smaller, than the GPS opening on the GW and It would then occupy the information display that is currently in that spot so a complete dash change over I would guess is needed. Not to mention the wiring requirements. But the biggest thing is Garmin handlebar mount GPSs are better units than any I know of that come factory mounted, HD included. Also can be upgraded or replaced with ease.