Not an F6B but I drove 300 miles with my Concours in the back of my tiny S-10 without issue. I mounted a Harbor Freight locking wheel chock which required drilling 4 holes through the bed. It's just a work truck so wasn't an issue. You could instead mount it to a piece of 3/4"x4'x8' plywood with carriage bolts sticking up from the bottom. Used giant tie-downs attached low and high.
Your Silverado is much bigger so it could probably handle the size of the B, but she's almost 1/2 ton so you'll need a helluva strong 12' ramp. Consider using a loading dock or some area that has an elevated area that you could back up to when loading.


Found this video when searching for "motorcycle loading fail". (I hate to see people fail, generally avoid these types of videos, but they can often be useful to see where mistakes can be made)