Not sure about a Toyo tire. But I would not run any car tire unless it a run flat. If air goes out of car tire on a bike and it is not a run flat. You are going to have 25 to 35 pound of rubber flapping around. You will crash no way to control the bike. I run a car tire on my F6B only thing I have ever riden a F6B with. I recommend a Pirelli P1 run flat. They work great!!