As the owner of a GL1500 approaching 200,000 miles I'll mention this: the engine may outlast other parts of the bike. Before the engine fails rubber and plastic parts may deteriorate, corrosion may appear in places, and various little parts may wear out. You'll find yourself replacing little stuff more and more often.
These are probably the most reliable motorcycles ever built. The VRCC still holds annual rallies and guys ride their Valks thousands of miles to attend. But eventually owners of very old, high mileage bikes seem to be proving a point rather than enjoying the ride.
You never know when something else may appear that grabs your attention. At Sturgis this year BMW introduced several new R18 models. They were so different that I really liked them. If I were in market I'd definitely give these a serious look. The Marshall Audio system was absolutely beyond belief.