if only between the Ultra and F6B then you have two distinct bikes with about as far apart in performance, and ergonomics as you can get.

The Ultra will not perform nearly as well or handle as well as the F6B. If you are into playing in the twisties, or twisting the wick then the F6B is a great bike.

Unless you spend big bucks the Harley wont even come close to running with this Honda.

The seating position is forward controls for the Ultra, and mid for the F6B. I still find that bothersome.

The ultra is easier to work on in that you don't have tupper wear to remove to get stuff done.

The F6B does not need much other than an air filter that is a real pain to do every 24,000 miles. Normal oil and filter can be done without removing anything.

Paint and finish are 100% better on any Harley than the F6B. The Harley will hold value much better than the F6B.